For people who, along with diet and a statin, need help lowering their bad cholesterol (LDL-C).
What is LEQVIO®?
Photo depicts actors.
Uniquely designed to help lower bad cholesterol with 2 doses a year*
Sometimes you need a little push to get you to where you want to be. That’s true when it comes to lowering bad cholesterol (LDL-C). Taking a statin alone may not be enough to get your numbers down. LEQVIO can help. LEQVIO is a cholesterol (LDL-C)-lowering injection that works with your liver’s natural process—alongside your statin and a healthy diet—to help get you to your goal.
*After 2 initial doses.
Teaming up with your doctor
LEQVIO is a medicine that’s given by injection for high bad cholesterol. You don’t have to do it yourself—your doctor or health care provider will do it for you. In fact, twice-yearly* LEQVIO can fit into your twice-yearly doctor visit schedule. You should continue taking your other cholesterol medicines, as instructed by your health care provider.
*After 2 initial doses.
Wondering what the dosing schedule is like with LEQVIO? This video will give you some details about the injection experience.
Taken with a statin, LEQVIO helps lower bad cholesterol with just 2 doses a year (after 2 initial doses) given by your doctor or health care provider.
Other injectable treatments require up to 12 or 26 doses a year (with or without statins), self-injected every month or every 2 weeks.
The comparison only relates to differences in dosing and how the drug is given, not to results or safety.
When statins aren't enough, adding LEQVIO is proven to lower bad cholesterol (LDL-C) and keep it low‡
A clinical study enrolled people with known heart disease who were on a statin and needed more help to lower their bad cholesterol (LDL-C). People who were treated with LEQVIO, in addition to their doctor-recommended statin dose, lowered bad cholesterol by ~50% and kept it low for 6 months between each dose vs placebo (a substance that doesn't contain any medication).
Clinical study information
These results are based on a study in which 1561 patients with atherosclerotic cardiovascular disease (ASCVD) were on a maximally tolerated statin with or without another cholesterol-lowering treatment—in addition to LEQVIO (781 patients) or a placebo (780 patients). Cholesterol levels were measured at the start of the study and compared with cholesterol levels 17 months later. Sixty percent of the patients were 65 years or older. LEQVIO was also studied in a similar clinical trial of 1617 patients with similar results.
‡People given LEQVIO lowered their bad cholesterol (LDL-C) more and kept it low during each 6-month dosing interval vs placebo (a substance that doesn’t contain any medication).
Individual results may vary.
LEQVIO helped people reach their goal
In a clinical study, 8 out of 10 people with known heart disease taking LEQVIO and a statin achieved the recommended bad cholesterol goal of less than 70 mg/dL vs 2 out of 10 people taking a statin and placebo at 17 months.
Any side effects of LEQVIO?
It’s important to understand the safety profile of your medication before you take it. For LEQVIO, injection site reactions were the most common side effect in clinical studies. Take a look at the numbers.
Side effect | People taking LEQVIO | People taking a placebo* |
Injection site reaction | 8% | 2% |
Joint pain | 5% | 4% |
Chest cold | 4% | 3% |
Side effects leading to | 2.5% | 1.9% |
*A substance that doesn't contain any medication.
In 3 clinical studies, 1833 people were treated with LEQVIO and 1822 people were treated with placebo.
Is LEQVIO right for you?
If you’ve struggled with lowering your bad cholesterol, despite eating healthy and exercising, LEQVIO may be able to help you finally get it lower. Of course, you’ll need to talk to your doctor to make the final decision. To learn more about LEQVIO, click the button for a helpful brochure.
FAQs
Definitions: ASCVD, atherosclerotic cardiovascular disease; LDL-C, low-density lipoprotein cholesterol.